Weak acid was used to hydrolysis the product produced by birch reduction and then the carbonyl group is protected through ketal. But the ketal could not still bear the conditions of aluminium isopropanoxide oxidation.
将伯奇还原的产物用弱酸水解,再用缩酮保护;用较温和的氧化剂重铬酸吡啶盐氧化,才能得到纯的氧化产物,而用异丙醇铝氧化时不能得到目标化合物。
参考来源 - 替勃龙的合成研究·2,447,543篇论文数据,部分数据来源于NoteExpress
以上来源于: WordNet
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