Objective:To investigate the relationship between the abnormality of the hepatocytic bile acid secretion and the formation of the gallstone.

目的：研究胆汁酸代谢异常与胆囊结石形成的关系。

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Under constant intravenous infusion of taurocholate to keep the bile acid pool steady, the effect of LHA injection of TRH on bile secretion was studied in rats with acute bile duct fistulae.

用具备急性胆瘘的大鼠在人工维持胆汁酸池恒定的条件下，观察LHA微量注射TRH对胆汁分泌的影响。

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Results:Chinese hippophae juice could decrease the rate of stone formation, promote synthesis and secretion of bile acid and protect liver cell from damages of stone forming bait.

结果：中华沙棘果汁可降低动物模型的成石率，并可促进胆汁酸的合成与分泌，保护肝细胞免受致石食饵的损伤。

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