Bigner spent years trying to make monoclonal antibodies against the mutant protein.

FORBES: Magazine Article

By then the surgeon Sampson, working with Darell Bigner, had devised a similar vaccine, and he began testing it in several small trials starting in 2002.

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It takes aim at an unusual mutation discovered in the late 1980s by Albert Wong and Bert Vogelstein at Johns Hopkins University and Darell Bigner at Duke.

FORBES: Magazine Article