To him, it was the biggest obstacle.

对他来说，这是最大的障碍。

youdao

Time, I realize, is the biggest obstacle to cooking for most people.

我意识到，对大多数人来说，时间是做饭的最大障碍。

youdao

What would you say is the biggest obstacle today to putting structures, equipment, people…anything really, into space?

你认为目前把结构、设备、人员等任何东西送上太空的最大障碍是什么？

youdao

What's the biggest obstacle to people getting tested and treated for HIV/AIDS in the MENA region?

VOA: standard.2010.07.07

What do you think is the biggest obstacle when people from other countries share each other's culture?

你认为来自不同国家的人们在彼此分享自己的文化时，最大的障碍是什么？

关于全球化 - SpeakingMax英语口语达人

I, honestly, time management has probably been my biggest obstacle as being a student.

实话说，也许管理时间是我做为一个学生最大的障碍。

时间管理很重要 - SpeakingMax英语口语达人

But the biggest obstacle to economic recovery is political indecision, especially concerning foreign policy.

ECONOMIST: Iran��s economy

But the biggest obstacle is likely to be Mr Redstone and Mr Karmazin themselves.

ECONOMIST: Two sharks in a fishbowl

When this journey began, I envisioned the biggest obstacle to my success would be physical.

CNN: Work out what matters most: Your mind