The role will be the biggest challenge of his acting career.

扮演这个角色将是他演艺生涯中最大的挑战。

《牛津词典》

Shirase'a biggest challenge was time.

Shirase 最大的挑战是时间。

youdao

My biggest challenge is learning how to behave at the dinner table.

我最大的挑战是学习如何在餐桌上举止得体。

youdao

He says the biggest challenge is jobs the disabled have the lowest employment rate of any minority group in the country.

VOA: special.2009.08.15

"The biggest challenge of getting life saving vaccines to poor countries is that there's no market.

VOA: special.2010.03.29

Right now the biggest challenge many face is access to credit - the ability to get loans at affordable rates.

VOA: standard.2009.03.16

But respecting the election result, no matter what it is, remains the biggest challenge of all.

ECONOMIST: Turkey and its army

The medic said a lack of sleep proved his biggest challenge on the trip.

BBC: Andrew Murray

Biggest challenge is getting the economy growing as rapidly as it needs to grow.

WHITEHOUSE: President Obama��s Town Hall in Cannon Falls, Minnesota