While the stores make big profits, it's the customer who loses out.

商店赚大钱，而吃亏的是顾客。

《牛津词典》

This means smaller banks can cream off big profits during lending booms.

这就意味着较小银行在贷款高峰期能将高额利润入私帐。

《柯林斯英汉双解大词典》

Big profits happen upstream.

产业链上游能够产生巨大的利润。

youdao

Indeed. Are you saying that this could be used as a formula for making some big profits in the market?

VOA: standard.2010.08.05

What do you think of big music companies and the profits created by selling music?

你对大的音乐公司和他们出售音乐创造的利润有什么看法？

音乐市场的变化 - SpeakingMax英语口语达人

"And it's being run for profit,big profits.

VOA: standard.2009.12.31

They saw big profits being made by flipping properties and wanted a piece of the action.

FORBES: Stocks are the New Bonds in 2011

The GSEs aimed to make big profits, and big bonuses, while backed by the government.

FORBES: The Volcker Rule Is in Better Shape That Some Think

The returns are highly uncertain, because the big profits (if any) are many years away.

ECONOMIST: Buttonwood: Backing greens with greenbacks | The