This time, the Lakers didn't blow a big lead.

这一次，湖人终于没让巨大优势再丧失。

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She has maintained a big lead in the opinion polls while doing little campaigning.

在这次的民意测试中，她少有游说活动却保持着领先的地位。

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While you may be handed a big lead, you will rarely be handed the entire match.

你可能获得一个较大得领先优势，但对手绝少会将整个比赛拱手向让。

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But the Shark Safe Project said the stated goal of "bringing in the big one" would lead to killing of the biggest sharks.

VOA: special.2009.06.16

Sometimes that subtle change can lead to a big change in the function of the protein.

有时候,蛋白质在结构上的小小改变,会导致其功能发生巨大变化

耶鲁公开课 - 生物医学工程探索课程节选

As I mentioned earlier it would lead, of course, to big cycles of boom and bust.

正如我之前提到它的导致,当然,经济繁荣与萧条的大循环

耶鲁公开课 - 美国内战与重建课程节选

Oklahoma City eliminated half of Houston's big lead before managing to stymie its own comeback.

NPR: Harden Powers Past Illness, Lifts Rockets 107-100

For those and other reasons, polls have given Rudy Giuliani a big lead in Florida.

NPR: Rudy Giuliani Counts on the Sunshine State

That would be helpful: Lula's big lead prompted further falls in Brazil's financial markets this week.

ECONOMIST: Brazil's presidential election