Over-fatigue is a big killer to many medium-aged people.

过劳是很多中年人的杀手。

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Traditionally, the big killer in Linux emulation was the clone system call.

传统上，Linux模拟中最难以处理的是clone系统调用。

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Three big questions need answering. First, could it turn into a global killer?

现在，有三大问题亟待解决：第一，这次会演变为全球性灾难吗？

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Apple may introduce the next big killer app iWallet along with iPhone 5.

FORBES: Apple's New iWallet Patent Hints At New Killer App

By all accounts, TB was not such a big killer in medieval times, when people stayed in their small villages.

WSJ: Matt Ridley on Infectious Diseases and Standards of Living | Mind & Matter

It's a big killer, and a big source of fear in women who are destined to die of something else.

FORBES: Magazine Article