This is a big advance.

这是个大的飞跃。

youdao

This represents a big advance in the way microscopes are used.

这代表我们在使用显微镜的方式上取得了巨大的进步。

youdao

That, he says, will be the next big advance in sinus treatment.

他说，这将会是未来治疗鼻窦炎的巨大的进步。

youdao

"We will get some vaccine at the beginning of the fall we won't be able to vaccinate everybody initially, so we'll be identifying priority groups, but because we had advance contracts for vaccine we'll get very big supplies through the fall and winter,".

VOA: standard.2009.07.31

Nathan Myhrvold, Reaching For The Big Advance (MIT Technology Review Sept 12, 2012).

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For Tom O'Brien , editor of the Gold Report, technicals present the strongest case for a big advance in gold.

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He scored a big advance from Pantheon, using that money to fund a classics factory, of which he is chief executive officer.

FORBES: Homemade Herodotus