Amyloid plaques form when a molecule called amyloid precursor protein (APP) is chopped up by two enzymes known as beta-secretase and gamma-secretase.

当一种叫淀粉样前体蛋白（APP）的分子被两种酶——分别叫作贝塔-分泌酶和伽玛-分泌酶——切断时就形成了淀粉样斑块。

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For the past decade there has been a lot of work on drugs called secretase inhibitors, which alter the activity of the enzymes that create amyloid beta-peptide 42.

在过去的10年里人们对被称为分泌酶抑制剂的药物进行了大量研究，这种药物可以改变酶类产生淀粉样贝塔-肽42的活动。

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Researchers in Iceland identified a rare genetic mutation that slows the activity of an enzyme called beta secretase, which is required to produce amyloid-beta.

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