This discovery raises the possibility that experts could find a way to detect flu early, and take preventative action before the worst effects develop.

这一发现为专家提早检测到流感病毒、在病情恶化之前采取预防措施提供了可能。

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Their retirement savings and home values fell sharply at the worst possible time: just before they needed to cash out.

他们的退休储蓄和房屋价值在最糟糕的时机急剧下跌：就在他们需要套现之前。

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By buying properties before the loans on them go bad, lenders can mask their worst bets.

在房贷变成不良贷款前购买房产，放贷人可以掩盖其最坏的损失程度。

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"The unemployment rate could,could, at its worst be over 10 percent before it starts to get better,"

VOA: standard.2009.04.02

If they see things accurately, there will be good countermeasures before the worst results come out.

FORBES: Screens In His Sights

With any luck, those of us of a certain age will be gone before the worst hits.

FORBES: Our Children's Budget

Before the worst financial crisis since the Great Depression, wages and incomes had been flat for the vast majority of Americans for a decade.

WHITEHOUSE: President Obama on the American Jobs Act in Emporia, Virginia | The White House