But Gleevac, too, can be bypassed by further mutations of BCR-ABL which allow the tumour cells to grow in the presence of the drug.

但它无法阻止BCR - ABL产生进一步变异后的编码蛋白，即使在用药情况下肿瘤细胞仍不断扩张。

youdao

There is already a targeted treatment for this disease. Gleevec, probably the most remarkable anti-cancer drug of the past decade, disables the protein encoded by another fused gene, BCR-ABL.

现在对这种病已有针对性疗法，Gleevec大体是过去十年中效果最显著的药物，它能使另一融合基因BCR-ABL的编码蛋白失去活性。

youdao

Objective:To study on relationship between of BCR/ABL fusion gene expression and TCM syndrome classification in the patient of chronic myelogenous leukemia(CML).

目的：探讨慢性粒细胞白血病（CML）患者BCR/ABL融合基因表达与中医辨证分型的关系。

youdao

It took advantage of X-ray crystallography that charted the precise three-dimensional structure of how Gleevec binds to Bcr-Abl.

FORBES: The Race Is On

The first being that you need to repeat this over and over during the treatment, very much like BCR-ABL. The second being that this technique has incredible low upstream and downstream processing and goes directly for the target.

FORBES: Gene Test For Pfizer Cancer Drug To Cost $1,500 Per Patient