Medicare could save hundreds of millions of dollars a year if everyone used the cheaper drug, Avastin, instead of the costlier one, Lucentis.

如果每个人都使用更便宜的药物安维汀，而不是更昂贵的雷珠单抗，那么医疗保障每年就可以节省数亿美元。

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The Food and Drug Administration has not approved Avastin for use in the eye, and using it rather than the alternative, Lucentis, might carry an additional, although slight, safety risk.

美国食品和药品管理局还没有批准阿瓦斯汀用于眼部治疗，使用它来代替雷珠单抗可能会产生额外的安全风险，尽管这一风险也许很轻微。

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The data also suggest that Avastin is potentially more toxic than chemotherapy.

数据还表明，相比化疗，阿伐斯汀具有更多的潜在毒性。

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In one study, 637 patients received standard chemotherapy plus radiation, and half also received Avastin.

NPR: Avastin Fails Studies In New Brain Tumor Patients

The biotech is actually restricting Avastin sales now to cut down on unapproved use.

FORBES: Magazine Article

However, researchers from Johns Hopkins University will release their findings of an Avastin vs.

FORBES: Patient Safety and 'Off-Label' Drug Use