Some studies showed that both the decrease of number and the dysfunction of CD4 + CD25 + regulatory T cells could lead to autoimmune diseases.
有研究表明CD4+CD25+Treg数量减少或功能异常均有可能导致自身免疫病的发生。
参考来源 - 内分泌与代谢病的免疫学发病机制研究·2,447,543篇论文数据，部分数据来源于NoteExpress
Scientists are also wary of potential side effects like auto-immune diseases and allergies.
但致癌或是得传染病的风险让此种方法的前景并不乐观。
TGN1412 was intended to fight leukemia, rheumatoid arthritis, and other auto-immune diseases.
TGN1412最初计划用于非白血性白血病、类风湿性关节炎以及其他自身免疫性疾病。
The cellular immune response mediated by NKG2D not only play an important role in immunosurveillance against tumor and infection, but also participate in some auto-immune diseases.
NKG2D介导的细胞免疫应答对于肿瘤或感染起着重要的免疫监视作用，同时与某些自身免疫性疾病也密切相关。
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