Background and Objective The goals of this study were to image oncogene c-erbB2 using 99mTc-radiolabelled antisense oligodeoxy-nucleotides（ASODN） to bind complementally target gene to diagnose breast cancer.
目的：本课题采用受休介导癌基因肿瘤反义显像诊断乳腺癌。
参考来源 - c·2,447,543篇论文数据，部分数据来源于NoteExpress
The inhibition rate of tumor growth of the PCNA-ASODN group was 64.5%.
结果 PCNA-ASODN治疗组大鼠胶质瘤的生长明显受到抑制，抑瘤率为64.5%。
Results The growth of human orbital rhabdomyosarcoma in nude mice was inhibited in the ASODN NP group obviously ( P< 0.05);
结果与其他两组相比，ASODN NP组肿瘤的生长明显受到抑制（P＜0.05）；
Conclusion ASODN can suppress endothelial cell growth and inhibit tumor angiogenesis possibly by specifically blocking VEGF expression in thyroid carcinoma.
结论A SODN可通过特异性封闭甲状腺癌细胞VEGF表达，抑制内皮细胞生长，干扰肿瘤血管生成。
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