Um, I'm not sure how to ask you this...

嗯，我不知该怎么问你这个…

《牛津词典》

Oliver, I hate to ask you this, but would you mind giving me a lift home?

奥利弗，我有个不情之请，我能搭你的便车回家吗？

youdao

Zach : Can I just ask you this by definition, property?

话说能向您请教一下“财产”是啥意思不？

youdao

"My friends,I ask you to join in this historic journey to have the courage to choose change.

VOA: special.2009.09.13

Then you might--well let me ask you this, what would happen if Google decided to buy up all of its shares?

你也可能,我来问问你,如果谷歌决定购回它所有的股票会怎么样呢

耶鲁公开课 - 金融市场课程节选

You can also turn this on its face a little bit and use this to ask a question.

你也可以对这个句型稍微做一下变形，用作疑问句。

It seems 课堂 - SpeakingMax英语口语达人

Let me ask you this, how many hospitals use a CYP450 affy chip SOP or an invader UGT1a1 assay ?

FORBES: A First Critique Of My DNA Sequencing Story

For entrepreneurs everywhere, I ask you this: How important is effective and grammatical communication to the success of your company?

FORBES: I Don't Tolerate Poor Grammar

Let me ask you this, how did you get your last job?

FORBES: A Call to Socialize