Two bad copies of the ApoE4 gene, for instance, can increase a person's chance of developing Alzheimer's disease by a factor of 10.

例如，两个坏的ApoE4基因副本，会把一个人得老年痴呆症的几率提高10倍。

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Previously, scientists knew of only one gene, called APOE4, which increases the risk of developing the most common form of the disease.

在此之前，科学家只知道一种称为载脂蛋白e4 (APOE4)的基因会增加患最普遍老年痴呆症的风险。

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The research by Oxford University has triggered a further study to look at why people with the APOE4 gene are more likely to develop Alzheimer's.

牛津大学的调查研究引发了关于为什么携带有apoe4基因的人更易得老年痴呆症的进一步探索。

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Other studies of patients who are ApoE4 carriers and non-carriers are under way.

FORBES: Pfizer And J&J Alzheimer's Drug Fails Late-Stage Trial

There are few clinical differences, experts say, between those with APOE4 and those without it once they develop the disease.

FORBES: Magazine Article

The trials include two in patients with APOE4 (an Alzheimer's disease risk factor) and two in patients without the gene.

FORBES: Magazine Article