AOAD is more common than previously thought and might even be the most common form of AD.

成年起病的亚历山大病较先前的认为更为常见，而且甚至可能是亚历山大病中最常见的类型。

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AOAD has a different clinical and neuroradiological presentation with respect to early-onset AD, as abnormalities are mainly concentrated in the brainstem-spinal cord junction.

成年起病的亚历山大病具有与早发型亚历山大病不同的临床和神经系放射学的表现，其异常主要集中在脑干脊髓接合处。

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We report detailed clinical and genetic data of 11 cases of AOAD, observed over a 4-year period, and a review of the previously reported 25 cases of genetically confirmed AOAD.

我们报道了11例成年起病的亚历山大病详细的临床和基因数据，进行了为期4年多的观察，并回顾了先前报道的25例通过遗传学证实的成年起病的亚历山大病。

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