As time went on, his ambition to be part of the U.S. Supreme Court faded in a miasma of alcohol and despair.

随着时间的推移，他要跻身美国最高法院的雄心壮志在酒精和绝望中消逝。

《柯林斯英汉双解大词典》

Fear and despair engulfed me.

恐惧和绝望吞没了我。

youdao

Hope and Despair Hope is what keeps life going.

希望与绝望希望是人生动力之源。

youdao

But the Navajo homeland is harsh country, where it's hard to find good-paying jobs and all too easy to fall sway to alcoholism and despair.

VOA: standard.2010.03.22

If the surprises are too great, then they induce overstrain and we throw away the book in frustration and despair.

如果令人惊讶之处过多，则会导致读者过劳,最后因失望或绝望而抛开它。

耶鲁公开课 - 文学理论导论课程节选

Plato's desire for a kind of radical makeover, of Athenian and Greek political institutions and cultures, grew out of his experience of political defeat and despair.

柏拉图想要彻底改变，雅典及希腊,政治制度及文化的欲望，来自他的,政治挫折及失望。

耶鲁公开课 - 政治哲学导论课程节选

She must have a robust constitution, he thought, immune to colds and despair, unsentimentally surviving.

NEWYORKER: The Valetudinarian

It portrays equal parts of hope and despair depicting people getting ready for their workdays.

FORBES: Clint Eastwood Didn't Make Karl Rove's Day

Indeed, since April 1, 115, 000 former workers have fled the work force in hopelessness and despair.

FORBES: Magazine Article