This disease is one of the most common infectious diseases , and a serious problem.

这种病是最常见的传染病之一，这是个严峻的问题。

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Most scientists agree that climate change is a serious problem that requires the attention of people and governments around the world.

VOA: special.2009.06.03

And off he goes, and he sulks in his tent for the next nine books, and this turns out to be a serious problem for them.

然后他真就走了,他回到自己的帐篷收拾东西,他这一走 问题就大了

耶鲁公开课 - 古希腊历史简介课程节选

He said it is a serious international problem that should be addressed broadly and can not be solved entirely by military means.

VOA: standard.2009.04.13

Therefore the availability of official documentation for sale to the highest bidder is a serious problem and deserves serious attention.

CENTERFORSECURITYPOLICY: Center For Security Policy

And while it is a serious problem that must be addressed, rebuilding the economy and raising employment and real wages is a great way to pay down that debt.

FORBES: False Assumptions in Obama's Deficit-Reduction Plan

The spread of weapons of mass destruction is a serious and actual problem and vigilance is important.

CENTERFORSECURITYPOLICY: Blowing Smoke About Making Deadly Gas