The F.D.A.’s new ruling, made Wednesday, resulted from a review of reports of “severe tissue injury, including gangrene, requiring amputation.”

研究过相关用药导致严重组织损伤(包括坏疽和截肢)的报告，本周三FDA通过了新法令。

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The vets determined the injury was life-threatening and that an amputation was called for.

兽医确定伤势危及生命并需要截肢。

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Objective To discuss the issue of the limb salvage versus the amputation of serious lower limb injury.

目的探讨严重下肢损伤的保肢与截肢问题。

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Louay Almokdad, a rebel spokesman, confirmed the attack to The Associated Press by phone and said the extent of the injury meant that amputation was likely, though he had not received confirmation it had been carried out.

NPR: Senior Syrian Rebel Leader Wounded In Bomb Attack

In a makeshift clinic there was a man with head injuries from shrapnel, another whose leg injury was most likely going to lead to an amputation.

CNN: Life and death under Syria's military onslaught

While many reports focused on amputation injuries, severe internal damage can occur with little or no external indication due to blast injury.

FORBES: Crumpled Elder Runner at Boston Marathon is Well