Objective:To evaluate the feasibility of transcatheter closure of patent foramen ovale(PFO)to prevent paradoxical embolism with Amplatzer occluder device.

目的：经导管封堵卵圆孔未闭（PFO）预防脑的矛盾栓塞并评价其疗效。

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Conclusions: Echocardiography can be used for guidance of Amplatzer occlusion device of ASD with solid edge without the measurement of balloon expanding size of ASD.

结论：对于周缘较硬的房缺，经食管超声心动图可直接指导封堵器大小的选择和封堵。

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The device, called the Amplatzer, is also being tested in adults to prevent strokes.

FORBES: Magazine Article

's Amplatzer is a fabric-mesh patch threaded through catheters to plug the hole.

NPR: Heart Repair Breakthroughs Replace Surgeon's Knife

Jude's device, called the Amplatzer PFO Occluder, is used to seal a flap-like passageway between the left and right atriums of the heart.

WSJ: Doctors Debate Whether Strokes Be Prevented With a Heart-Plug Procedure