EGFR gene copy number alteration and mutation are highly variable and scientists have been challenged to define their prognostic significance in triple-negative breast cancer.

EGFR基因拷贝数的改变和突变有很大的差异，科学家试图定义其在三阴性乳腺癌中的预后意义。

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Therefore, the dwarf mutation in X. helleri is caused by the developmental defect in spinal column, and the vertebral malformation underlies the body type alteration anatomically.

因而推测，剑尾鱼的侏儒突变是由于脊椎的发育缺陷所致，椎体异常是其体型变化的结构基础。

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