... allopurinol nucleotide别嘌呤醇核苷酸 alloreactivity同种异体反应性 allorecognition同种(异体)识别 ...
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Up to now, there is no report about the role of the alloreactivity of NK cells in TRIM.
截止目前,NK细胞的异源性反应在TRIM中的作用研究尚无文献报道。
参考来源 - 异源反应性NK细胞对输血相关免疫抑制作用的初步研究Background and ObjectiveDonor killer cell immunoglobulin-like receptors (KIR) cluster and recipient human leukocyte antigen (HLA) mismatching induce NK cell alloreactivity in allo-hematopoietic stem cell transplantation.
背景与目的供者杀伤细胞免疫球蛋白样受体(KIR)基因簇和受者人白细胞抗原(HLA)不匹配诱导的NK细胞异体反应可改善异基因造血干细胞移植的治疗效果。
参考来源 - KIR基因簇KIR3DL1、KIR2DL1、KIR2DL2/3多态性研究·2,447,543篇论文数据,部分数据来源于NoteExpress
I think these findings about the basis of alloreactivity expand our understanding of this process.
我想有关同种异体反应性基础的这些发现拓宽了我们对于该过程的理解。
Christopher Garcia have established how the structure of receptors on the surface of t cells enables this dual recognition, a phenomenon known as alloreactivity.
Christopher Garcia领衔的科研小组揭示了T细胞表面受体结构为何能双重识别,该现象也称为同种异体反应性。
CONCLUSION: in mouse allogeneic bone marrow transplantation, alloreactivity NK cells prevents GVHD, reduces graft rejection, and promotes engraftment and reconstituting of hematopoiesis.
结论:NK细胞抑制小鼠异基因骨髓移植中的GVHD和移植排斥,促进骨髓植入及造血重建。
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