"The three laureates have accomplished what many scientists thought impossible, namely to determine the three- dimensional structure of the molecular machine that makes all the proteins in a cell, the so-called ribosome,"
VOA: standard.2009.10.07
His conjecture, made in 1904, was that in this four-dimensional world, all closed three-dimensional surfaces that are simply connected could be transformed to look like a three-dimensional sphere.
Unfortunately, the processing required to perform the integration of all 51 two-dimensional images into a three-dimensional one is so demanding that the computers Dr Kanade has available take five days to produce ten seconds-worth of video.