Compare three different fish oil materials on fatty acids composition,content and quality indexes, choose menhaden oil for the synthesis of ethyl esters by alkaline catalyst. After single factor and response surfaces experiment, The best technics condition is obtained: reactant mol ratio(alcohol/ fish oil)6:1,temperture 75℃~77℃, reaction time 2 hours, alkali catalyst concentration 0.8N-1.0N, the yield of ethyl esters was 96%.
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