Objective: To investigate the amplification and protein expression of AIB1 gene, as well as its clinical significance, in ovarian cancer.

目的：探讨AIB1基因在卵巢癌中的基因扩增与蛋白表达及其临床意义。

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The researchers, from Baylor College of Medicine in Houston, found that when two proteins, called AIB1 and HER-2, are present in high levels in the cells of women who have had breast cancer, their tumours are resistant to the cancer-fighting effects of tamoxifen.

BBC: Tamoxifen