Tamoxifen has been shown to reduce the recurrence of ER-positive breast cancer when used after primary treatment.

在一期治疗之后服用，Tamoxifen可以降低雌激素阳性乳腺癌的复发。

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The study’s primary endpoint was objective response rate, the percentage of patients who experienced complete or partial cancer shrinkage or disappearance after treatment.

研究主要终点是客观缓解率，治疗后经受完全或部分癌症皱缩或消失患者的百分率。

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However, there is no data demonstrating that liver resection before LT, which can be used either as a bridge treatment or as a primary treatment, improves the survival after LT.

但是，目前还没有数据显示，作为一个过度或者初步的治疗，肝移植前进行肝切除是否可以改善移植后的存活率。

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The companies decided to end the program for developing the compound, called Dimebon, after it failed to meet two primary endpoints in a phase 3 trial studying its use with the existing treatment Aricept in patients with mild-to-moderate Alzheimer's.

WSJ: Medivation, Pfizer Alzheimer's Drug Fails to Meet Study Goals