The invention relates to a method to compounding 2-molindone that includes the following steps: using aniline as raw material, adding NaOH that the mol ratio is 1.0:2.0-1.0, adding solvent, taking reaction with chloroacetic chloride to form acylation material of aniline, and the mol ratio of chloroacetyl chloride is 2.0-1.0:1.0;
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