Climate change is a significant cause.

气候变化是一个重要原因。

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This is bad for the team and is a significant cause of project failure.

对于整个小组来说，这样是不好的，这是项目失败的一个很重要的原因。

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A significant cause of disability in older Americans is, simply, falling.

造成美国老年人残疾的一个重要原因就是摔倒。

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Spotted fever in purples for example, which we call measles, was a significant cause of death as was the plague, which we don't have anymore, thank goodness.

拿紫色斑疹热作为例子,我们也把这种病称作麻疹,它是导致死亡的主要原因,就好像瘟疫,而现在不会再这样了,感谢上帝

耶鲁公开课 - 生物医学工程探索课程节选

Stress was a significant cause of teachers being off sick according to the figures.

BBC: 21,000 teaching days lost to stress in Wales in 2009

Health experts say once unknown bacteria including campylobacter, commonly found in chicken, are now thought to be a significant cause of such disorders as Guillain-Barre Syndrome, which can cause paralysis.

CNN: Is the government fighting food poisoning?

Andrew Husband, principle lecturer in pharmacy at the University of Sunderland and lead on the Gateshead study said allergies were a significant cause of avoidable adverse drug reactions among hospital in-patients each year.

BBC: Patients should be asked about allergies on admission