In Donnelley's directory plant in Dwight, for example, new computers alert operators feeding 14 presses when a roll of paper is about to run out--a process they eyeballed until six months ago.

FORBES: Companies & Strategies

Designed for rough concepting and creative brainstorming, Inkling bridges the gap between paper sketching and digital drawing by giving users at the front end of the creative process a way to rough-out ideas with real ink on paper and capture their concepts digitally so that they can be later refined on their computer.

ENGADGET: Wacom Inkling smart pen does drawing the old-fashioned way -- sort of (video)

"It is very hard to enforce replication before publication without causing significant delays in the review process, " which could lessen a paper's relevance, said Pinelopi Goldberg, AER editor and an economist at Yale University.

WSJ: Spreadsheet Slips Not Economists' Only Problem