I have a difficult case to deal with.

我遇到一件难对付的事情。

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It can be difficult for public figures to win a libel case.

公众人物要赢得诽谤诉讼是有难度的。

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This is a very difficult case.

这病真缠手。

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Others disagreed. In any case, it was not a good time to argue it was the Great Depression, and times were difficult.

VOA: special.2009.12.29

Now let's imagine a somewhat more difficult case.

现在想象一下,一个更加复杂的问题。

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Bedfordshire Police said it had been "a difficult case" because it had taken time to encourage key witnesses to make formal statements.

BBC: Delaney Brown death: Kyle Beckford guilty of murder

But the authors acknowledge it is a difficult case to make.

BBC: Python skin trade worth a billion - and often illegal

With weak evidence and a difficult case, they pressured KPMG in effect to indict itself, go into deferred prosecution mode, and participate in the case against individual defendants.

FORBES: Justice 'Deferred'