对于脱落病例采用末次观察推进法(LOCF)处理数据。计量资料采用配对t检验比较组内前后差异，两组治疗前后的变化采用方差分析(ANOVA)进行比较，计数资料采用x 2检验或其他...
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研究结果以末次观察推进法(locf,lastobservationcarriedforward)为基础进行判断。
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Last observation carry forward LOCF 最近一次观察的结转
These criteria are met in all three studies, when the last observation carried forward (LOCF) method was used to impute the 52week results from subjects who discontinued early.
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