Methods:The plasma and cerebrospinal fluid(CSF) levels of 5 HT, 5 HIAA(5 hydroxyindoleacetic acid) and NE(norepinephrine) were measured in 48 patients with hypertension cerebral strode by fluorometry.
方法：用荧光法测定4 8例脑卒中患者血浆和脑脊液5- HT，5-羟吲哚乙酸（5- HIAA） ，去甲肾上腺素（NE）水平。
Conclusion: Oubining can prevent vomiting induced by DDP and its mechanism is relative to the decreases of DDP, 5-ht and 5-hiaa concentrations in cerebrospinal fluid and medullary tissues.
结论：呕必宁对DDP所致呕吐反应具有防治作用，其机制可能与降低猫脑脊液中ddp的浓度，降低脑脊液、脑组织中5 - HT、5 - HIAA含量有关。
The changes in 5-ht and 5-hiaa contents were more complex.
羟色胺和5—羟吲哚乙酸含量变化较复杂。
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