有大量的研究表明它们并不是很好的标志物，因为甲胎蛋白和其他两个标志物也仅仅在晚期癌症表达更加常见。
There is a good deal of data to suggest that they are not very good markers because alpha fetoprotein and these other two markers are also more common and more commonly expressed in advanced cancers.
第二点是关于应用这些标志物的资料证实，活组织检查表明不是癌症的某些东西，多数情况下是早期疾病的问题。
The second point is that data on the use of these markers to prove that something you biopsy is not cancer is mainly a problem with early stage disease.
虽然GPC1作为胰腺癌诊断的生物标志物仍需要在更大的患者群进行验证，但这一发现展示了外泌体诊断癌症的强大力量。
Although GPC1 as a biomarker of pancreatic cancer need to be validated in larger patient cohorts, this finding exemplifies the power of utilizing exosomes for cancer diagnose.
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