依托泊甙(etoposid,vepesid,鬼臼乙叉苷,足草乙苷,VP16)和替尼泊甙(teniposide,鬼臼噻吩苷,特尼泊苷,VM26)为植物西藏鬼臼(Podophyllus emodii Wall)的有效成分鬼臼毒素(podophyllotoxin)的半合成衍生物。
应用硼氢化钠还原法合成三个硒代鬼臼毒素衍生物。
Three derivatives of selenoylpodophyllotoxin were composed with the reduce method. The synthetic process is temperate;
表鬼臼毒素2″,3″二脱氧糖苷的新型胺衍生物,其制备方法其作为药物的应用及其抗癌治疗的应用。
Amine derivatives of epipodophyllotoxin 2', 3'-dideoxyglycosides, preparation method therefor and use thereof as drug and for treating cancer.
鬼臼毒素及其衍生物是一类具有显著生理活性的木脂素类化合物,其主要生理活性表现为抗肿瘤活性及抗病毒活性。
Podophyllotoxin as well as its derivatives exhibit a pronounced biological activity mainly as antitumor agents, which is a good source of the aryltetralin lignan.
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