目的观察透骨消痛胶囊干预骨性关节炎软骨下骨重塑的作用及机制。
Objective to observe the effect of Tougu Xiaotong granula (TGXT) on subchondral bone remodeling and investigate the mechanism.
口服双磷酸盐类药物是治疗该病的主要方法,但长期使用这些药物可能会抑制骨重塑,从而导致罕见的骨折,其使用风险令人担忧。
Oral bisphosphonates have become a mainstay of treatment, but concerns have emerged that long-term use of these drugs may suppress bone remodeling, leading to unusual fractures.
可能有重塑性骨破坏。
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