...项目(2004BA720A33-1) 【分类号】: R698.2 【正文快照】: 尿激酶型尿纤溶酶原激活因子(urokinase plas-minogen activator,uPA)是一种丝氨酸蛋白水解酶,为机体中广泛分布的内源性物质。
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目的:探讨尿激酶型纤溶酶原激活因子的蛋白表达与上皮性卵巢癌生物学行为的关系。
Objective: To identify the significance of urokinase-type plasminogen activator expression in patients with epithelial ovarian carcinoma.
以上结果说明,小鼠胚胎着床过程中胰蛋白酶及纤溶酶原激活因子等水解蛋白酶的活性起着重要作用。
These results suggested that proteolytic activities were involved in implantation, some proteinases such as trypsin and plasminogen activator had important functions during trophoblast invasion.
研究者还发现2型纤维蛋白溶酶原激活因子抑制物(PAI2)(一种丝氨酸蛋白酶抑制物)抑制结核杆菌感染的巨噬细胞内的膜联蛋白- 1的蛋白水解作用。
The researchers also found that plasminogen activator inhibitor type 2 (PAI2), a serine-protease inhibitor, inhibited proteolytic truncation of annexin-1 in macrophages infected with M. tuberculosis.
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