目的:评价辐射诱发的染色体畸变作为癌患风险评估指标的可行性。
Purpose:To evaluate the probability of using chromosome aberrations induced by irradiation as a indicator of future cancer risk.
方法不同辐射体核素诱发的畸变产额变化,通过骨髓细胞和精原细胞染色体畸变测定。
Methods The changes of aberration yields induced by different radiators were determined using chromosomal aberration assay in both bone marrow cells and spermatogonia.
本文主要对辐射诱发染色体畸变和微核的形成与细胞分裂周期的关系作了综述和分析,并对微核细胞率作为辐射损伤的细胞学指标进行了评价。
This paper reviewed the relationship between chromosomal aberrations at the different stages of mitotic cycle and the mechanism of chromosomal aberrations and micronuclei induced by radiation.
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