实验结果表明N-乳糖酰壳聚糖是ASGPR的特异性配基,对肝细胞具有“主动”靶向作用,可作为肝靶向载体。
The results indicated that N-Lactosyl-Chitosan was a good ligand for ASGPR, and could be used as hepatic targeting carrier of antitumor drugs.
结论:重组表达载体PGL3 - DF 3 - DTA能对DF 3阳性的乳腺癌细胞产生特异性杀伤作用。
Conclusion: Recombinant expression vector PGL3-DF3-DTA could produce specific lethal effect on human breast cancer cell line of DF3 positive.
免疫毒素是近年来新兴的一种特异性靶向治疗药物,由毒素蛋白和载体两部分构成。
Immunotoxin is a novel class of targeted agents in recent years, which is composed of toxin fragment and antibody or cytokine.
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