诱饵受体(decoy receptor)也能特异性地识别并结合某种配基,但不引起细胞信号转导以及细胞代谢的改变。趋化因子(chemokine)是一类具有
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Osteoprotegerin which was discovered by Simonet in 1997 is a decoy receptor of RANKL regulating bone metabolism. Osteoprotegerin can bind to RANKL competing with RANK and block the binding of RANK and RANKL, which result in dysmaturity of osteoclast.
骨保护素(osteoprotegerin,OPG)是1997年由Simonet等6发现出一种能够调节骨代谢的糖蛋白RANKL的诱饵受体,它可以和RANK竞争与RANKL结合,从而阻断RANK与RANKL的结合,导致破骨细胞分化成熟障碍。
参考来源 - 重组人骨保护素对聚乙烯颗粒刺激破骨细胞功能的影响·2,447,543篇论文数据,部分数据来源于NoteExpress
剩余三种类型的蛋白称为诱饵受体。
他们发现“肿瘤诱饵”DCR3第三号诱饵受体会让癌细胞扩散更快,这在未来有助于协助患者选择正确的癌症疗法。
They found that the "tumor bait" DCR3 No. 3 decoy receptor allow faster spread of cancer cells, which help to assist patients in the future to choose the right cancer treatment.
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