因此，药物穿透主要是由非解离型来完成的。
Thus, drug penetration may be attributed mostly to the un-ionized form.
非解离型部分通常为脂溶性，很容易透过细胞膜扩散。
The un-ionized form is usually lipid soluble and diffuses readily across cell membranes.
高度蛋白结合药物的入脑通透速率缓慢，慢得使解离型弱酸或弱碱的通透速率几乎为零。
The penetration rate into the brain is slow for highly protein-bound drugs and can be so slow for the ionized form of weak acids and bases as to be virtually nonexistent.
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