肝星状细胞的激活、表型改变并分泌大量的细胞外基质是肝纤维化发生的中心环节。
The activation of hepatic stellate cell phenotype change and secretion of extracellular matrix of liver fibrosis is the central link.
这种肿瘤被连续地移植了好几代，在每一个我们观察到逐步加快肿瘤的生长没有明显的表型改变。
Such tumours were serially transplanted for several generations, in each of which we observed progressively faster tumour growth without significant phenotypic alterations.
结论D MN引起大鼠肝窦内皮细胞损伤及其表型改变可能是其诱导肝纤维化重要的始动机制之一。
Conclusions the damage and phenotypic alteration of the hepatic sinusoidal endothelium may be a vital issue triggering the liver fibrosis induced by DMN.
应用推荐