血纤维蛋白和血小板一起形成血栓。血友病就是因为遗传上缺乏一种凝血胶原引起的。

Fibrin and platelets combine to form a clot. Hemophilia is caused by a hereditary lack of one of the clotting factors.

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总的来说，血液系统异常可以导致止血因子缺乏、肾功能衰竭、尿毒症、血小板减少症，这些变化可以促进出血，但是可以抵消高凝状态带来的一系列改变。

Collectively, this can create a haemostatic defect, renal failure, uremia, thrombocytopenia which all favour bleeding but are offset due to the changes that led to hypercoagulability.

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