用两种乳腺癌细胞株模型评价纳米粒介导的细胞药物释放动力学和机理及纳米粒包囊阿霉素的治疗效果。
Kinetics and mechanism of nanoparticle-mediated cellular drug delivery and therapeutic efficacy of nanoparticle-encapsulated doxorubicin were evaluated in two model breast cancer cell lines.
另外,我们的模型整合机制使药物从聚合物基质中释放的过程可以被定量分析。
Furthermore, our model incorporates mechanisms by which the processes underlying drug release from a polymer matrix can be quantitatively analyzed.
方法采用无膜溶出模型,考察释放面积、振荡频率对眼用凝胶溶蚀及药物释放的影响。
Methods The non-membrane model was introduced to observe the influence on the drug release and gel erosion for surface area and shaking frequency.
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