方法:以包封率和平均粒径为评价指标,采用星点设计-效应面法优化醇质体处方中大豆磷脂、药物和无水乙醇的最佳配比。
METHODS Taking encapsulated ratio and average diameter as evaluation index to optimize the best matching of soybean phospholipid, drug and absolute alcohol in ethosomes.
方法以微囊的药物包封率为制备工艺优化指标,利用复凝聚法,通过正交实验得出微囊的最佳制备工艺条件。
Methods the orthogonal experimental design adopting the standard of drug encapsulation was applied to optimize the preparation procedure of the microcapsules by the complex coacervation method.
不同制备条件对微球药物包封率的影响程度较小。
The drug incorporation efficiency was affected in a narrow range by the conditions.
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