前言: 0 引言基因治疗是当前肿瘤治疗的前沿课题,其中“药物敏感基因(drug sensitivity gene)”的应用尤为引人嘱目,单纯疱疹病毒胸苷激酶(HSV-tk)/丙氧鸟苷(GCV)系统是目前最常用的药敏基因治疗系统。
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在所研究的基因中,有87种在一系列实验室检查中对于化疗药物紫杉醇特别敏感。
Of the genes studied, 87 were particularly sensitive to the chemotherapy drug Taxol in a series of lab tests.
基因表达谱形成了乳腺癌复发和药物敏感性的分子预测器。
Gene-expression arrays have generated molecular predictors of relapse and drug sensitivity in breast cancer.
降低胰岛素抵抗——开发的药物通过调节胰岛素敏感基因降低胰岛素抵抗。胰岛素抵抗是引发2型糖尿病的原因之一。
Reducing Insulin Resistance – A medicine in development addresses insulin resistance, an underlying cause of type 2 diabetes, by modulating genes responsible for insulin sensitization.
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