...研究 ］介绍的统计方法,以粒径＜1 μm的粒子分布百分数、微球的载药量(Drug loading,DL)、药物包封率(Drug trapping eff iciency,DTE)为指标,对微球制备工艺进行综合考察。
基于4个网页-相关网页
The NLC exhibited improved drug entrapment efficiency and drug loading capacity by increasing OA content. The in vitro drug release rates were enhanced with the increasing of OA content.
随着油酸含量的增加,NLC的药物包封率、载药量、药物释放速率随之增加。
参考来源 - 脂质纳米载体的细胞转运与抗肿瘤药效研究To overcome the disadvantages such as lower drug entrapment efficiency (EE) and loading (DL) of lipid nanospheres prepared by conventional solvent diffusion method, a solvent diffusion method in drug saturated aqueous system was developed.
为了克服采用传统溶剂扩散法制备脂质纳米粒存在的药物包封率与载药量较低等缺点,研究出一种新的溶剂扩散法。 新的溶剂扩散法采用外相为药物饱和溶液系统。
参考来源 - 尼莫地平脂质纳米粒制备工艺、理化性质及其大鼠体内药动学的研究·2,447,543篇论文数据，部分数据来源于NoteExpress
不同制备条件对微球药物包封率的影响程度较小。
The drug incorporation efficiency was affected in a narrow range by the conditions.
利用扫描电镜和紫外光谱考察了内相聚合物浓度和搅拌速度对微球粒径和药物包封率的影响。
The effects of polymer concentration and agitation rates on the size of microspheres and drug incorporation efficiency were studied by scanning electronic microscopy (SEM) and UV-spectrophotometry.
本发明方法建立的给药系统具有载药范围广、药物包封率高及稳定性好的特点，并可降低药物毒性。
The drug delivery system established by the method has the characteristics of wide drug-carrying range, high drug envelopment rate and good stability and can reduce drug toxicity.
应用推荐