药物代谢研究是新药开发中不可缺少的一项。
Metabolic study is an indispensable part to the development of new drugs.
目的：建立一种简便、经济、高效分离原代大鼠肝细胞的方法，适用于体外药物代谢研究。
Objective: to develop a convenient, inexpensive and efficient method for isolation of functional primary rat hepatocytes, which can be used successfully for in vitro metabolism study.
巴格列酮已经经过一系列临床前期药效药理学、安全药理学、药代动力学或毒性动力学和药物代谢研究的评估。
Balaglitazone has been evaluated in a series of preclinical efficacy pharmacology, safety pharmacology, pharmacokinetic/toxicokinetic, and drug metabolism studies.
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