目的：创建缓释植入剂局部给药治疗系统的药动学模型。
Objective:To establish the pharmacokinetic model for a target therapeutic system of sustained-release implants.
本发明应用了药动学模型和药效学模型来确定最适的药物制剂和最适的施用参数。
A pharmacokinetic and pharmacodynamic model is employed to determine optimum drug formulations and optimum parameters for administration.
参数法包括十个药动学模型和三种药效学模型，可以同时求算药动学和药效学参数；
Parametric method which based on the theory of "effect compartment" suggested by Sheiner (1979) et al includes ten PK models and three PD models.
应用推荐